A medical-meteorological weather assessment using hybrid spatial classification of synoptic and meteorological data was done. Empirical models for assessment as well as for forecast of medical-meteorological weather type at the seaside climatic zone in Palanga were developed. It was based on the data of meteofactors (atmospheric pressure, relative humidity, temperature, oxygen density in atmosphere, cyclone fronts, etc.) as well as on the occurrence of meteotropical reactions of cardiovascular function collected during 8-year period. The empirical models allow objectively assess and forecast 3 types of medical-meteorological weather types: favourable, unfavourable and very unfavourable weather. Classification model assessed favourable weather type in 56.1%, unfavourable in 31.7% and very unfavourable in 12.2%, while forecast was of favourable weather type in 52.4%, unfavourable in 46% and very unfavourable in 1.6% of days. Developed model enables more precise weather estimation and forecast meteotropical reactions promoting development of preventive measures of cardiovascular complications for reduction of negative weather impact on health in coronary artery diseases patients.